Be it produced in microbiological culture or purified from plants and other raw materials.
Our equipment allows us to produce and further process or subsequently purify a variety of different toxins (Upstream and downstream processing).
In the fermenter, we can produce cultures up to a maximum of 30 L in one batch and subsequently process them further in the downstream.
For this process we have established a plethora of methods for filtration and chromatographic purification. But we can also develop a new method in cooperation with you and according to your specifications. This also applies to the required analytical procedures whether it should be an immunochemical assay or tested in cell culture.
Are you interested in a cooperation to develop a toxin as a biopharmaceutical and bring it to market?
We have experience in production, purification, analysis, but also in regulatory issues in this context.
You benefit from
We run immuno-chemical, physical and biological methods for characterisation, quantification and potency testing of toxins and antitoxins/antibodies.
We kindly ask you to contact us to jointly identify which method or which combination of methods would be the most suitable approach for your needs.
Our methods at a glance:
Botulinum neurotoxin type A1 with a molecular mass of 150, type E3 complex, inactivated toxins or Tetanus neurotoxin. We have various toxin types and purities as lab reagents available ex stock.
Our bacterial strain collection includes many types and subtypes of Clostridium botulinum, Clostridium tetani, Clostridium perfringens and many more. Shouldn’t you find what you are looking for in our catalogue, we will be happy to produce and purify it exclusively for you.
Mostly available ex stock
Types B1, B3
Clostridium botulinum neurotoxin (complex)
Types B1, B3
Clostridium botulinum neurotoxin (mosaic toxins)
(Culture supernatants, partially purified by filtration)
Clostridium tetani (150)